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Shelf Life Validation

Accelerated and real-time ageing to establish product shelf life

Shelf Life Validation Services

Shelf life validation establishes the expiry date of a medical device. Working to ASTM F1980 and ISO 11607, we provide accelerated ageing and real-time ageing services, deriving shelf life from a defensible ageing model to support registration and market release.

Shelf Life Validation

Testing Standards

ASTM F1980

Standard guide for accelerated aging of sterile barrier systems for medical devices

ISO 11607

Packaging for terminally sterilized medical devices

ICH Q1A

Stability testing of new drug substances and products

YY/T 0681

Test methods for sterile medical device packages

Testing Projects

Accelerated ageing

Accelerated ageing at elevated temperature to derive shelf life

Real-time ageing

Real-time ageing validation under ambient conditions

Package integrity

Sterile barrier system integrity before and after ageing

Seal strength

Change in seal strength before and after ageing

Sterility testing

Retention of sterility before and after ageing

Stability study

Stability study protocol design and shelf life determination strategy

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